diff --git a/packages/playwright-core/src/client/browser.ts b/packages/playwright-core/src/client/browser.ts
index 19df307510..8ded087173 100644
--- a/packages/playwright-core/src/client/browser.ts
+++ b/packages/playwright-core/src/client/browser.ts
@@ -65,6 +65,8 @@ export class Browser extends ChannelOwner<channels.BrowserChannel> implements ap
   async _newContextForReuse(options: BrowserContextOptions = {}): Promise<BrowserContext> {
     for (const context of this._contexts) {
       await this._browserType._onWillCloseContext?.(context);
+      for (const page of context.pages())
+        page._onClose();
       context._onClose();
     }
     this._contexts.clear();
diff --git a/packages/playwright-core/src/server/dispatchers/browserContextDispatcher.ts b/packages/playwright-core/src/server/dispatchers/browserContextDispatcher.ts
index ba644d06e0..1c5168c776 100644
--- a/packages/playwright-core/src/server/dispatchers/browserContextDispatcher.ts
+++ b/packages/playwright-core/src/server/dispatchers/browserContextDispatcher.ts
@@ -270,8 +270,7 @@ export class BrowserContextDispatcher extends Dispatcher<BrowserContext, channel
       this._subscriptions.delete(params.event);
   }
 
-  override _dispose() {
-    super._dispose();
+  override _onDispose() {
     // Avoid protocol calls for the closed context.
     if (!this._context.isClosingOrClosed())
       this._context.setRequestInterceptor(undefined).catch(() => {});
diff --git a/packages/playwright-core/src/server/dispatchers/debugControllerDispatcher.ts b/packages/playwright-core/src/server/dispatchers/debugControllerDispatcher.ts
index e1a73b145e..801ab35d0f 100644
--- a/packages/playwright-core/src/server/dispatchers/debugControllerDispatcher.ts
+++ b/packages/playwright-core/src/server/dispatchers/debugControllerDispatcher.ts
@@ -79,8 +79,7 @@ export class DebugControllerDispatcher extends Dispatcher<DebugController, chann
     await this._object.closeAllBrowsers();
   }
 
-  override _dispose() {
-    super._dispose();
+  override _onDispose() {
     this._object.dispose();
   }
 }
diff --git a/packages/playwright-core/src/server/dispatchers/dispatcher.ts b/packages/playwright-core/src/server/dispatchers/dispatcher.ts
index 7f689383a1..d82fccd914 100644
--- a/packages/playwright-core/src/server/dispatchers/dispatcher.ts
+++ b/packages/playwright-core/src/server/dispatchers/dispatcher.ts
@@ -102,8 +102,12 @@ export class Dispatcher<Type extends { guid: string }, ChannelType, ParentScopeT
     this._connection.sendDispose(this);
   }
 
+  protected _onDispose() {
+  }
+
   private _disposeRecursively() {
     assert(!this._disposed, `${this._guid} is disposed more than once`);
+    this._onDispose();
     this._disposed = true;
     eventsHelper.removeEventListeners(this._eventListeners);
 
diff --git a/packages/playwright-core/src/server/dispatchers/pageDispatcher.ts b/packages/playwright-core/src/server/dispatchers/pageDispatcher.ts
index 7d62a70eea..34da4c5e30 100644
--- a/packages/playwright-core/src/server/dispatchers/pageDispatcher.ts
+++ b/packages/playwright-core/src/server/dispatchers/pageDispatcher.ts
@@ -299,9 +299,10 @@ export class PageDispatcher extends Dispatcher<Page, channels.PageChannel, Brows
     this._dispatchEvent('frameDetached', { frame: FrameDispatcher.from(this, frame) });
   }
 
-  override _dispose() {
-    super._dispose();
-    this._page.setClientRequestInterceptor(undefined).catch(() => {});
+  override _onDispose() {
+    // Avoid protocol calls for the closed page.
+    if (!this._page.isClosedOrClosingOrCrashed())
+      this._page.setClientRequestInterceptor(undefined).catch(() => {});
   }
 }
 
diff --git a/packages/playwright-core/src/server/page.ts b/packages/playwright-core/src/server/page.ts
index f781bb8991..266366c214 100644
--- a/packages/playwright-core/src/server/page.ts
+++ b/packages/playwright-core/src/server/page.ts
@@ -612,6 +612,10 @@ export class Page extends SdkObject {
     return this._closedState === 'closed';
   }
 
+  isClosedOrClosingOrCrashed() {
+    return this._closedState !== 'open' || this._crashedPromise.isDone();
+  }
+
   _addWorker(workerId: string, worker: Worker) {
     this._workers.set(workerId, worker);
     this.emit(Page.Events.Worker, worker);
diff --git a/tests/library/debug-controller.spec.ts b/tests/library/debug-controller.spec.ts
index 8ef3622b36..fc1f224335 100644
--- a/tests/library/debug-controller.spec.ts
+++ b/tests/library/debug-controller.spec.ts
@@ -20,10 +20,12 @@ import { createGuid } from '../../packages/playwright-core/lib/utils';
 import { Backend } from '../config/debugControllerBackend';
 import type { Browser, BrowserContext } from '@playwright/test';
 
+type BrowserWithReuse = Browser & { _newContextForReuse: () => Promise<BrowserContext> };
 type Fixtures = {
   wsEndpoint: string;
   backend: Backend;
-  connectedBrowser: Browser & { _newContextForReuse: () => Promise<BrowserContext> };
+  connectedBrowserFactory: () => Promise<BrowserWithReuse>;
+  connectedBrowser: BrowserWithReuse;
 };
 
 const test = baseTest.extend<Fixtures>({
@@ -41,16 +43,24 @@ const test = baseTest.extend<Fixtures>({
     await use(backend);
     await backend.close();
   },
-  connectedBrowser: async ({ wsEndpoint, browserType }, use) => {
-    const oldValue = (browserType as any)._defaultConnectOptions;
-    (browserType as any)._defaultConnectOptions = {
-      wsEndpoint,
-      headers: { 'x-playwright-reuse-context': '1', },
-    };
-    const browser = await browserType.launch();
-    (browserType as any)._defaultConnectOptions = oldValue;
-    await use(browser as any);
-    await browser.close();
+  connectedBrowserFactory: async ({ wsEndpoint, browserType }, use) => {
+    const browsers: BrowserWithReuse [] = [];
+    await use(async () => {
+      const oldValue = (browserType as any)._defaultConnectOptions;
+      (browserType as any)._defaultConnectOptions = {
+        wsEndpoint,
+        headers: { 'x-playwright-reuse-context': '1', },
+      };
+      const browser = await browserType.launch() as BrowserWithReuse;
+      (browserType as any)._defaultConnectOptions = oldValue;
+      browsers.push(browser);
+      return browser;
+    });
+    for (const browser of browsers)
+      await browser.close();
+  },
+  connectedBrowser: async ({ connectedBrowserFactory }, use) => {
+    await use(await connectedBrowserFactory());
   },
 });
 
@@ -231,3 +241,27 @@ test('should pause and resume', async ({ backend, connectedBrowser }) => {
   await backend.resume();
   await pausePromise;
 });
+
+test('should reset routes before reuse', async ({ server, connectedBrowserFactory }) => {
+  const browser1 = await connectedBrowserFactory();
+  const context1 = await browser1._newContextForReuse();
+  await context1.route(server.PREFIX + '/title.html', route => route.fulfill({ body: '<title>Hello</title>', contentType: 'text/html' }));
+  const page1 = await context1.newPage();
+  await page1.route(server.PREFIX + '/consolelog.html', route => route.fulfill({ body: '<title>World</title>', contentType: 'text/html' }));
+
+  await page1.goto(server.PREFIX + '/title.html');
+  await expect(page1).toHaveTitle('Hello');
+  await page1.goto(server.PREFIX + '/consolelog.html');
+  await expect(page1).toHaveTitle('World');
+  await browser1.close();
+
+  const browser2 = await connectedBrowserFactory();
+  const context2 = await browser2._newContextForReuse();
+  const page2 = await context2.newPage();
+
+  await page2.goto(server.PREFIX + '/title.html');
+  await expect(page2).toHaveTitle('Woof-Woof');
+  await page2.goto(server.PREFIX + '/consolelog.html');
+  await expect(page2).toHaveTitle('console.log test');
+  await browser2.close();
+});