diff --git a/packages/playwright-core/src/server/webkit/wkPage.ts b/packages/playwright-core/src/server/webkit/wkPage.ts
index 1ae8d23082..a8a007162b 100644
--- a/packages/playwright-core/src/server/webkit/wkPage.ts
+++ b/packages/playwright-core/src/server/webkit/wkPage.ts
@@ -185,6 +185,7 @@ export class WKPage implements PageDelegate {
     ];
     if (this._page.needsRequestInterception()) {
       promises.push(session.send('Network.setInterceptionEnabled', { enabled: true }));
+      promises.push(session.send('Network.setResourceCachingDisabled', { disabled: true }));
       promises.push(session.send('Network.addInterception', { url: '.*', stage: 'request', isRegex: true }));
     }
     if (this._page._browserContext.isSettingStorageState()) {
@@ -723,6 +724,7 @@ export class WKPage implements PageDelegate {
     const enabled = this._page.needsRequestInterception();
     await Promise.all([
       this._updateState('Network.setInterceptionEnabled', { enabled }),
+      this._updateState('Network.setResourceCachingDisabled', { disabled: enabled }),
       this._updateState('Network.addInterception', { url: '.*', stage: 'request', isRegex: true }),
     ]);
   }
diff --git a/tests/page/interception.spec.ts b/tests/page/interception.spec.ts
index 140346de69..c381e9f6e3 100644
--- a/tests/page/interception.spec.ts
+++ b/tests/page/interception.spec.ts
@@ -172,3 +172,21 @@ it('should not break remote worker importScripts', async ({ page, server, browse
   await page.goto(server.PREFIX + '/worker/worker-http-import.html');
   await page.waitForSelector("#status:has-text('finished')");
 });
+
+it('should disable memory cache when intercepting', async ({ page, server }) => {
+  let interceted = 0;
+  await page.route('**/page.html', route => {
+    ++interceted;
+    void route.fulfill({
+      body: 'success'
+    });
+  });
+  await page.goto(server.PREFIX + '/page.html');
+  expect(await page.locator('body').textContent()).toContain('success');
+  await page.goto(server.EMPTY_PAGE);
+  await expect(page).toHaveURL(server.EMPTY_PAGE);
+  expect(interceted).toBe(1);
+  await page.goBack();
+  await expect(page).toHaveURL(server.PREFIX + '/page.html');
+  expect(interceted).toBe(2);
+});